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In vitro studies have demonstrated that DFO can inhibit the degradation of type II collagen in osteoarthritis cartilage while also reducing the expression of inflammatory factors such as MMP-1, MMP-13, IL-1, and TNF- (Tchetina et al., 2016)

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As a general rule for: - Hydrogen-dominant SIBO we like to use berberine with neem or oil of oregano - Methane-dominant SIBO we like to use allicin with oil of oregano or neem